• Assess first for faecal impaction.
• Polyethylene glycol with electrolytes is first line for disimpaction, using an escalating oral regimen. Add a stimulant laxative if disimpaction is unsuccessful after an adequate trial.
• After disimpaction, continue polyethylene glycol as maintenance treatment and titrate to produce regular soft stools. Treatment commonly continues for months, not days, and should not be stopped abruptly.
• If polyethylene glycol is unavailable or poorly tolerated, lactulose 1 to 3 mL/kg/day PO in divided doses can be used, adjusted to stool response.
• Combine medication with regular toilet sitting after meals, positive reinforcement, adequate dietary fibre and normal fluid intake.
• Diet alone is insufficient treatment for established functional constipation.